Yalkın ÇALIK, Safinaz ATAOĞLU, Ersun BAŞ, Selma YAZICI, Ali Erdem BAKİ, Metin YAVUZ

Departments of Physical Medicine and Rehabilitation, Medical Faculty of Düzce University, Düzce, Turkey

Keywords: Adult-onset still's disease, hemophagocytic syndrome, hemophagocytosis


Hemophagocytic syndrome is a fatal and life-threatening syndrome characterized by pancytopenia and multiple organ failure. It can frequently be seen in childhood as a primary or familial condition. In adults, it occurs secondarily. In etiology, wide range of factors are related to this syndrome. Adult-onset Still's disease seems to be one of the systemic rheumatological diseases that cause this syndrome. In our literature review, we found few studies related to this syndrome. In this article, we report a 40-year-old female patient who had been treated with the diagnosis of Adultonset Still's disease for four years in our clinic and who developed hemophagocytic syndrome during her follow-ups.