Microscopic Polyangiitis With Positive Hantaan Virus-Specific Immunoglobuline M Antibody Caused by Cross Reaction: A Case Report

Diao ZONGLI, Zhang AIHUA, Wang GANG, Liu WENHU

Department of Nephrology, Beijing Friendship Hospital, Capital Medical University, Beijing, China

Keywords: Cross reaction, Hantaan virus, hemorrhagic fever with renal syndrome, microscopic polyangiitis

Abstract

Patients with microscopic polyangiitis may have an immune disorder and generate antibodies which may cross-react with foreign proteins. In this article, we report a 71-year-old female case of microscopic polyangiitis patient with positive Hantaan virus-specific immunoglobuline M antibodies without hemorrhagic fever with renal syndrome. In this case, an immune disorder may generate antibodies that cross-reacting with Hantaan virus antigen, resulting in positive Hantaan virus-specific immunoglobuline M antibody measurements.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.