Sibel Özbudak Demir1, Göknur Karahan1, Gülümser Aydın2, Füsun Köseoğlu1

Keywords: Fibrodysplasia ossificans progressiva

Abstract

Fibrodysplasia (myositis) ossificans progresiva (FOP) is a hereditary mesodermal tissue characterized by progressive ossification of striated muscle, tendon, ligament, fasciae, aponeurose and occasionally skin. The pattern of inheritance remains unknown. Indeed, most reported cases are the result of spontaneous mutations. In this article we present two cases with FOP and reviewed the literature.