Case Report

Idiopathic Interstitial Pneumonia as a Possible Cause of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Case Report

Volume 33 · Issue 1 Publish Date: March 31, 2018
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Hiroshi OIWA
Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan image/svg+xml
Katsuhiro OOI
Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan image/svg+xml
Tetsu OYAMA
Department of Rheumatology, Oyama Clinic, Hiroshima, Japan image/svg+xml
Eiji SUGYAMA
Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan image/svg+xml
Hiroshi OIWA, Katsuhiro OOI, Tetsu OYAMA, & Eiji SUGYAMA. (2018). Idiopathic Interstitial Pneumonia as a Possible Cause of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Case Report. Archives of Rheumatology, 33(1), 089–092. https://doi.org/10.5606/ArchRheumatol.2018.6532
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Abstract

There are conflicting data to date on the causal relationship between idiopathic interstitial pneumonia and antineutrophil cytoplasmic antibody (ANCA): (1) myeloperoxidase-ANCA may play a pathogenetic role in pulmonary fibrosis, or (2) pulmonary fibrosis may induce production of the antibody. In this article, we describe a case of an elderly female patient with microscopic polyangiitis that developed after positive conversion of myeloperoxidase-ANCA during the course of idiopathic interstitial pneumonia. Our experience as well as similar case reports may suggest that idiopathic interstitial pneumonia may induce production of ANCAs and even ANCA-associated vasculitis.

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Published In
Journal Archives of Rheumatology
Volume / Issue Volume 33 · Issue 1
Pages 089-092
History
Published Online March 31, 2018
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Hiroshi OIWA
Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan
Katsuhiro OOI
Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan
Tetsu OYAMA
Department of Rheumatology, Oyama Clinic, Hiroshima, Japan
Eiji SUGYAMA
Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan
Cite this Article
Hiroshi OIWA, Katsuhiro OOI, Tetsu OYAMA, & Eiji SUGYAMA. (2018). Idiopathic Interstitial Pneumonia as a Possible Cause of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Case Report. Archives of Rheumatology, 33(1), 089–092. https://doi.org/10.5606/ArchRheumatol.2018.6532
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