Abstract
The efficacy and safety of anti-tumor necrosis factor-alpha drugs have been shown in active ankylosing spondylitis cases that are resistant to traditional disease-modifying antirheumatic drugs. However, it is well known that these drugs may cause some complications as reactivation of tuberculosis and various hematologic malignancies. In this article, we report a 40-year-old male patient with ankylosing spondylitis who developed Philadelphia chromosome-positive acute lymphoid leukemia after treatment with tumor necrosis factor-alpha inhibitors.
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Article Info
Published In
Journal
Archives of Rheumatology
Volume / Issue
Volume 30 · Issue 4
Pages
349-352
History
Published Online
December 31, 2015
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
Affiliations
Füsun GEDİZ ÖZDEMİRKIRAN
Department of Hematology, Katip Çelebi University, Atatürk Training and Research Hospital, İzmir, Turkey
Bahriye Kadriye PAYZIN
Department of Hematology, Katip Çelebi University, Atatürk Training and Research Hospital, İzmir, Turkey
Eyüp ÇOBAN
Department of Internal Medicine, Katip Çelebi University, Atatürk Training and Research Hospital, İzmir, Turkey
Korhan Barış BAYRAM
Department of Physical Medicine and Rehabilitation, Katip Çelebi University, Atatürk Training and Research Hospital, İzmir, Turkey
Betül KÜÇÜKZEYBEK
Department of Pathology, Katip Çelebi University, Atatürk Training and Research Hospital, İzmir, Turkey
Cite this Article
Füsun GEDİZ ÖZDEMİRKIRAN, Bahriye Kadriye PAYZIN, Eyüp ÇOBAN, Korhan Barış BAYRAM, & Betül KÜÇÜKZEYBEK. (2015). Acute Lymphoid Leukemia After Anti-TNF-alpha Treatment: A Case Report and Review of the Literature. Archives of Rheumatology, 30(4), 349–352. https://doi.org/10.5606/ArchRheumatol.2015.5669
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