Original Article

An Assessment of Flow-Mediated Dilatation in Behçet's Disease

Volume: 27 Issue: 3, September 2012 Publish Date: September 30, 2012
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DOI
Ruken YÜKSEKKAYA
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey image/svg+xml
Fatih ÇELİKYAY
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey image/svg+xml
Fatih KOÇ
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey image/svg+xml
Çağlar DENİZ
Department of Cardiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey image/svg+xml
Erkan GÖKÇE
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey image/svg+xml
Mehmet Murat FIRAT
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey image/svg+xml
Jale YÜKSEK3
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey image/svg+xml
Ruken YÜKSEKKAYA, Fatih ÇELİKYAY, Fatih KOÇ, Çağlar DENİZ, Erkan GÖKÇE, Mehmet Murat FIRAT, & Jale YÜKSEK3. (2012). An Assessment of Flow-Mediated Dilatation in Behçet’s Disease. Archives of Rheumatology, 27(3), 152–157. https://doi.org/10.5606/tjr.2012.026
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Abstract

Objectives: This study aims to evaluate the early development of atherosclerosis in patients with Behçet's disease (BD) using flow-mediated dilatation (FMD) method under Doppler ultrasonography (US).

Patients and methods: Thirty patients with BD and 25 healthy volunteers were included. Doppler US was used to measure the basal and post-reactive hyperemic diameters, peak systolic velocities, resistivity indices, and blood flow volumes of the brachial arteries. Flowmediated dilatation was defined as the percentage of difference between the post-reactive hyperemic and basal diameters.

Results: The mean FMD value of the BD group (10.8±12.7%) was significantly lower compared to the control group (26±18.6%). No statistically significant difference in other parameters was found between the groups.

Conclusion: Flow-mediated dilatation under Doppler US is simple and effective non-invasive method for predicting the early development of atherosclerosis in patients with BD.

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Article Info
Published In
Journal Archives of Rheumatology
Volume / Issue Vol. 27 No. 3 (2012): The Archives of Rheumatology
Pages 152-157
History
Published Online September 30, 2012
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Affiliations
1
Ruken YÜKSEKKAYA
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey
2
Fatih ÇELİKYAY
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey
3
Fatih KOÇ
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey
4
Çağlar DENİZ
Department of Cardiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey
5
Erkan GÖKÇE
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey
6
Mehmet Murat FIRAT
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey
7
Jale YÜKSEK3
Department of Radiology, Medical Faculty of Gaziosmanpaşa University, Tokat, Turkey
Cite this Article
Ruken YÜKSEKKAYA, Fatih ÇELİKYAY, Fatih KOÇ, Çağlar DENİZ, Erkan GÖKÇE, Mehmet Murat FIRAT, & Jale YÜKSEK3. (2012). An Assessment of Flow-Mediated Dilatation in Behçet’s Disease. Archives of Rheumatology, 27(3), 152–157. https://doi.org/10.5606/tjr.2012.026
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