Case Report

Mikulicz’s Disease With Immune Thrombocytopenia: A New Immunoglobulin G4-Mediated Disorder and Literature Review

Volume 34 · Issue 3 Publish Date: September 30, 2019
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DOI
Shu LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China image/svg+xml
Cong DENG
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China image/svg+xml
Jinwei CHEN
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China image/svg+xml
Fen LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China image/svg+xml
Shu LI, Cong DENG, Jinwei CHEN, & Fen LI. (2019). Mikulicz’s Disease With Immune Thrombocytopenia: A New Immunoglobulin G4-Mediated Disorder and Literature Review. Archives of Rheumatology, 34(3), 343–347. https://doi.org/10.5606/ArchRheumatol.2019.7070
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Abstract

Mikulicz’s disease (MD), an immunoglobulin G4 (IgG4)-related disease, is a fibrosis-associated inflammatory disease characterized by painless bilat- eral swelling of lacrimal and salivary glands. Although thrombocytopenia is associated with many rheumatologic disorders, it is rare in IgG4-related MD. This novel study aims to report a rare case of IgG4-related MD complicated with severe autoimmune thrombocytopenia without any hemato- logical malignancies and review all cases of IgG4-related disease associated with thrombocytopenia in the literature.

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Published In
Journal Archives of Rheumatology
Volume / Issue Volume 34 · Issue 3
Pages 343-347
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Published Online September 30, 2019
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Shu LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Cong DENG
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Jinwei CHEN
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Fen LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Cite this Article
Shu LI, Cong DENG, Jinwei CHEN, & Fen LI. (2019). Mikulicz’s Disease With Immune Thrombocytopenia: A New Immunoglobulin G4-Mediated Disorder and Literature Review. Archives of Rheumatology, 34(3), 343–347. https://doi.org/10.5606/ArchRheumatol.2019.7070
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